Professor Andrew Clegg is Theme Lead for the Health and Care in our Ageing Society theme.
He is also Head of Ageing and Stroke Research at the University of Leeds and an Honorary Consultant Geriatrician at Bradford Royal Infirmary. Professor Clegg is Director of the global Ageing Research Trialist (ART) Collaborative, which was established to support individual participant data meta-analyses in ageing research, and Co-Director of Health Data Research UK (HDR UK) North.
Professor Clegg leads a substantial portfolio of ageing-related research, with a particular focus on frailty as a complex and problematic expression of multimorbidity in later life, as well as medicines optimisation. He has secured approximately £44 million in research funding as lead or co-investigator. This includes leadership of a research theme focused on improving care for older people with frailty within the NIHR Applied Research Collaboration Yorkshire and Humber, and a workstream within the NIHR Leeds Biomedical Research Centre (BRC) Musculoskeletal Theme.
His research expertise spans clinical trials of interventions, prognostic modelling using routine data, applied epidemiology, and evidence synthesis. He is Chief Investigator for the NIHR-funded Personalised Care Planning for Older People with Frailty (PROSPER) Research Programme, the Community Ageing Research 75+ study, and the Wellbeing in Later Life in Bradford longitudinal cohort study with routine data linkage. He is also Co-Chief Investigator for the NIHR HTA-funded Comprehensive Geriatric Assessment for Older People with Heart Failure and Frailty (CHART) trial.
Professor Clegg previously led the development, validation, and national implementation of the multi-award-winning electronic frailty index (eFI), which is recommended in the NICE Multimorbidity Guideline. Developed using data from approximately one million UK patients within the ResearchOne and THIN primary care research databases, the eFI has had a significant impact on UK health policy and was selected as a National Medical Schools Council Impact Case Exemplar in 2022.
BackgroundWellbeing in later life is not experienced equally. Factors such as frailty, ethnicity, gender, income and social circumstances can combine to influence how well people age and the care and...
Optimising Structured Medication Reviews for Older People with Severe Frailty and Care Home Residents to Reduce Overprescribing and Associated Inequalities BackgroundOverprescribing is a growing challenge in healthcare and can increase...
Which older people are most likely to benefit from community-based comprehensive geriatric assessment (CGA)? An individual participant data meta-analysis of trials BackgroundMaintaining independence in later life is a major priority...