Individual participant data meta-analysis (IPDMA) – a new frontier in multiple long-term conditions (MLTC) research

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5th November 2025

12:30 pm

– 1:30 pm

Zoom

Part of Webinar Series

Individual clinical trials rarely analyse and report results from a multiple long-term conditions (MLTC) perspective – they look at the whole population. Individual participant data (IPD) meta-analysis has the potential to transform evidence-based care for people with MLTC.

IPDMA involves the collection, preparation, validation and analysis of the original individual-level trial data recorded for each participant. It increases statistical power, enabling investigation of characteristics that predict treatment effects (e.g. MLTC, frailty, disability, gender, ethnicity, socioeconomic position).

This seminar will introduce the concept of IPDMA and how it can be applied to MLTC, including an example of treatments for diabetes.

Our Guest Speakers:

Andrew Clegg, Professor of Geriatric Medicine
Tom Crocker, Associate Professor of Stroke Care
Peter Hanlon, Clinical Senior Research Fellow (General Practice & Primary Care)

Guest Speakers Bio:

Professor Andrew Clegg is Head of Ageing and Stroke Research at the University of Leeds and Honorary Consultant Geriatrician at Bradford Royal Infirmary. He is Director of the global Ageing Research Trialist (ART) collaborative, established to support individual participant data meta-analysis in ageing research, and Co-Director for Health Data Research UK (HDRUK) North.

Dr Tom Crocker is an applied health researcher at Leeds Institute of Health Sciences. He uses qualitative, quantitative and mixed methods for applied health research, with expertise in complex interventions and evidence synthesis.

Dr Peter Hanlon is a General Practitioner and a Clinical Research Fellow based in General Practice and Primary Care. He is interested in using quantitative methods to understand health needs and clinical management of people with multiple long-term health conditions and frailty.

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