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The association between antihypertensive treatment and serious adverse events by age and frailty: A cohort study.

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Antihypertensives are effective at reducing the risk of cardiovascular disease, but limited data exist quantifying their association with serious adverse events, particularly in older people with frailty. This study aimed to examine this association using nationally representative electronic health record data.

References: Sheppard JP, Koshiaris C, Stevens R, Lay-Flurrie S, Banerjee A, Bellows BK, Clegg A, Hobbs FDR, Payne RA, Swain S, Usher-Smith JA, McManus RJ. The association between antihypertensive treatment and serious adverse events by age and frailty: A cohort study. PLoS Medicine 2023;20(4):e1004223. https://doi.org/10.1371/journal.pmed.1004223

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Sheppard JP, Koshiaris C, Stevens R, Lay-Flurrie S, Banerjee A, Bellows BK, Clegg A, Hobbs FDR, Payne RA, Swain S, Usher-Smith JA, McManus RJ.

Head of Academic Unit for Ageing and Stroke Research, NIHR Research Professor of Geriatric Medicine

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